Re: AW: [HSF] the little heat exchanger for arch op´s

[Rwmfglycar at aol.com]

In a message dated 12/21/2006 3:03:14 A.M. Eastern Standard Time,  
battr at medizin.uni-leipzig.de writes:

Do
anyone rewarm with greater difference? And higher temperatures?.  We try to
avoid brain ödema.



There is another reason for keeping the rewarming gradient under control.  
Dave Donald (Scottish veterinarian who was part of the team that brought the  
Mayo Gibbon machine to clinical use in 1955) showed in 1959 that gas bubbles  
coming out of solution during rewarming reached measurable levels when the  
temperature gradient was too high. I remember a number of 4 deg.  Celsius,  and 
several cc. accumulating in a fairly short period of time,  but Dave was 
assuming that any amount of gas bubbles in the  arterial blood was too much. He did 
not have a test that could tell the  damage that might be done in the brain for 
instance.
Bob