Re: AW: [HSF] the little heat exchanger for arch op´s

[prasannasimha]

That is basically why we also do not maintain a gradient of more than 
8-10 Degrees C.
I usually teach this to my perfusion students by heating coca cola.
Prasanna
Rwmfglycar at aol.com wrote:
>  
> In a message dated 12/21/2006 3:03:14 A.M. Eastern Standard Time,  
> battr at medizin.uni-leipzig.de writes:
>
> Do
> anyone rewarm with greater difference? And higher temperatures?.  We try to
> avoid brain ödema.
>
>
>
> There is another reason for keeping the rewarming gradient under control.  
> Dave Donald (Scottish veterinarian who was part of the team that brought the  
> Mayo Gibbon machine to clinical use in 1955) showed in 1959 that gas bubbles  
> coming out of solution during rewarming reached measurable levels when the  
> temperature gradient was too high. I remember a number of 4 deg.  Celsius,  and 
> several cc. accumulating in a fairly short period of time,  but Dave was 
> assuming that any amount of gas bubbles in the  arterial blood was too much. He did 
> not have a test that could tell the  damage that might be done in the brain for 
> instance.
> Bob
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