[HSF] More Bad News About Trasylol

[prasannasimha]

2 months back a patient who had undergone transfusions 2 years back and 
with no h/o sexual exposure or any high risk behavior came back HIV 
positive and we interpreted it as a possible transmission during the 
window period. She was HIV negative at the time of surgery.
Now that its adding to the situational mess !!! Transfuse and be damned 
- Aprotinin and be damned !! It may not be HIV tomorrow but some new 
virus which we have not identified !! remember that serum samples from 
the 60's are now shown to be HIV +ve and we did not know about the 
disease then !!
Prasanna

 Hgrmd at aol.com wrote:
> Bob,
>   I think Trasylol definitely ameliorates the coagulopathy associated  with 
> CPB.  Given the fact that I'm on track to do only about 5% stand alone  CABG's 
> this year, I'm always looking for ways to decrease my need for blood  
> products.  However, as I said earlier, years ago I independently reached  the 
> conclusion that my patients receiving aprotinin had a higher incidence of  ATN.  I 
> hadn't noticed higher rates of CVA, CHF, or MI's.  I noticed  this problem 
> regardless of the dose used of aprotinin.  In addition, yes I  am fearful of getting 
> sued by the judicial gladiators intent on separating me  from my hard earned 
> assets.  With this latest round of bad news in the  press, I think surgeons 
> who use the drug do so at their own peril.  I can  honestly tell you that if I 
> was to have a complex cardiac procedure (e.g.,  Bentall), I wouldn't want the 
> surgeon to aprotinin.  I'd rather get  transfused than to possibly end up with 
> no kidneys.
> Hal
> _______________________________________________
> OpenHeart-L mailing list
>
> Send postings to:
>  OpenHeart-L at lists.hsforum.com
>
> To UNSUBSCRIBE, to CHANGE email address, or to view archives:
> http://mmp.cjp.com/mailman/listinfo/openheart-l
>
> All messages transmitted by the OpenHeart-L are subject to the policies and 
> disclaimers posted at:
> http://www.hsforum.com/listdisclaim
> -----------------------------------------
>
>
>