[HSF] More Bad News About Trasylol

[Ben Bidstrup]

Prasanna,
Here they are.

1.	Koch, C.G., et al., Transfusion in coronary artery bypass 
grafting is associated with reduced long-term survival. Ann Thorac 
Surg, 2006. 81(5): p. 1650-7.

2.	Koch, C.G., et al., Morbidity and mortality risk associated 
with red blood cell and blood-component transfusion in isolated 
coronary artery bypass grafting. Crit Care Med, 2006. 34(6): p. 
1608-16.

3.	Koch, C.G., et al., Persistent effect of red cell transfusion 
on health-related quality of life after cardiac surgery. Ann Thorac 
Surg, 2006. 82(1): p. 13-20.

There is also one from UK last year.

Kuduvalli, M., et al., Effect of peri-operative red blood cell 
transfusion on 30-day and 1-year mortality following coronary artery 
bypass surgery. Eur J Cardiothorac Surg, 2005. 27(4): p. 592-8.


>Ah Michael I  had a feeling you will jump in !! Can you give the 
>Cleveland clinic quote - (wrt to the 7 % blood transfusion risk) -I 
>cannot seem to get hold of it.
>Dr Levinson, I still feel pdf files should be allowed. I think that 
>copyright laws still allow us too circulate them privately for 
>educational prurposes. This is freely done in the critical care list 
>and Gas net (the Anesthesiologists list). In fact now many journals 
>allow open access after say 6 months to a year after publications.
>Prasanna
>Michael Firstenberg wrote:
>>Hal,
>>Since I am always on the other side of your coin.  What about all 
>>of the risks of blood transfusions?  There is plenty of data that 
>>relates blood product usage to increased risk of adverse outcomes. 
>>How do you respond to the Catfish type that say - "if you had used 
>>aprotinin/amicar/etc then my client would not have gotten ......"?
>>
>>Michael
>>
>>for my Bentall - give me Amicar.
>>for my redo infected Bentall - hmmm, might take the risk......
>>
>>
>>On Sep 30, 2006, at 2:17 PM, Hgrmd at aol.com wrote:
>>
>>>Prasanna,
>>>   We haven't heard from Claudia, our in house hematologist, in  awhile.
>>>Perhaps she can comment.  However, my impression is that the 
>>>blood bank, at least
>>>in the U.S., is about as safe as it has ever been.  I  agree that new blood
>>>borne diseases may arise in the future, but the risk of 
>>>aprotinin-associated
>>>ATN is immediate and real.
>>>Hal
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-- 
Ben Bidstrup FRACS FRCSEd FEBCTS
Consultant Cardiothoracic Surgeon