[HSF] More Bad News About Trasylol

[Ben Bidstrup]

>Ben,
>   With your pioneering work with aprotinin as well as your extensive 
>clinical experience with the drug, do you believe that aprotinin 
>increases the  odds
>of ATN?  If so, do you agree that postop ATN is associated with at  least a
>20-30% mortality?
>Hal
>_______________________________________________
No

and

New renal dialysis after cardiac surgery  is associated with a higher 
mortality in most of the reviews I have looked at. Not all ATN 
results in dialysis - we often sit it out if the electrolytes etc. do 
not go haywire. It is the dialysis that seems to increase the risks.

Whether  aprotinin contributes to that is not certain.
-- 
Ben Bidstrup FRACS FRCSEd FEBCTS
Consultant Cardiothoracic Surgeon