[HSF] More Bad News About Trasylol

[Ben Bidstrup]

Hal,
It was only CABG patients.

>Ben,
>   This dose dependent reduction in survival after transfusion could 
>be explained by the patient with an acute type A dissection who 
>requires 30 units of blood.  Did the blood transfusions cause his 
>death, or was it the profuse bleeding or hypoperfusion which 
>eventually produced multisystem organ failure?  I think it's 
>extremely difficult to subtract out contributions of other factors 
>in a patient's demise.
>Hal
>
>
>-----Original Message-----
>From: benjamin.bidstrup at bigpond.com
>To: OpenHeart-L at lists.hsforum.com
>Sent: Sun, 1 Oct 2006 10:47 AM
>Subject: Re: [HSF] More Bad News About Trasylol
>
>
>>John,
>>  I completely agree. It is ridiculous to state that each unit of packed
>>cells increases the mortality 7%. If so, I would have had cases who did fine
>>in spite of a 140% predicted mortality. The 82 yo lady I'm supposed to do
>>tomorrow has a HCT of 34. She needs a redo CABG (1 graft), 
>>mitral >and tricuspid
>>repairs. The EF is normal. I suspect I'll use 5 or 6 units of blood. Do
>>you think I just increased her predicted mortality an additional 30% in
>>addition to the inherent 15% risk? Neither do I.
>>Hal
>>_______________________________________________
>Read the papers. None state that each unit of RBC increases the risk 
>by 7% - but that there is a dose dependent reduction in survival 
>after transfusion.
>-- Ben Bidstrup FRACS FRCSEd FEBCTS
>Consultant Cardiothoracic Surgeon
>_______________________________________________
>OpenHeart-L mailing list
>
>Send postings to:
>OpenHeart-L at lists.hsforum.com
>
>To UNSUBSCRIBE, to CHANGE email address, or to view archives:
>http://mmp.cjp.com/mailman/listinfo/openheart-l
>
>All messages transmitted by the OpenHeart-L are subject to the 
>policies and disclaimers posted at:
>http://www.hsforum.com/listdisclaim
>-----------------------------------------
>________________________________________________________________________
>Check out the new AOL.  Most comprehensive set of free safety and 
>security tools, free access to millions of high-quality videos from 
>across the web, free AOL Mail and more.
>_______________________________________________
>OpenHeart-L mailing list
>
>Send postings to:
>  OpenHeart-L at lists.hsforum.com
>
>To UNSUBSCRIBE, to CHANGE email address, or to view archives:
>http://mmp.cjp.com/mailman/listinfo/openheart-l
>
>All messages transmitted by the OpenHeart-L are subject to the policies and
>disclaimers posted at:
>http://www.hsforum.com/listdisclaim
>-----------------------------------------


-- 
Ben Bidstrup FRACS FRCSEd FEBCTS
Consultant Cardiothoracic Surgeon