[HSF] Trip to Croatia

Ani Anyanwu anianyanwu at hotmail.com
Sat Apr 7 18:22:30 EDT 2007


Thank you very much Dr Frater on your analysis of paravalvar leakage. You are indeed an amazing source of knowledge and inspiration for young and inexperienced students of surgery like myself and I keep several of your contributions (such as this) for future reference. Your comment about lack of ingrowth and permanent dependency on the suture for ring security is interesting and likely explains some late leaks that occur with a continuous technique. Could future changes to the left ventricle or annulus also impact on the security of an implanted valve? Could the fractured suture occur secondary to such change (the tension on the continuous suture is presumably more than on the individual interrupted sutures)?

Based on your analysis though within a semi-continuous suture line with 3 or 4 independent sutures (strictly speaking they are not even independent as they are tied to one another) there are 3 reasons why the suture line could have failed
i) Knots were not tied properly
ii) Either of your listed factors 1 to 6 were in operation or
iii) Inadvertent damage to the suture material during surgery.

My question therefore is as before - if either of these had caused the leak in one of the 3 or 4 segments of continuous prolene, then is it safe to assume the same factors are not in operation - or might in future be in operation - in the seemingly unaffected prolene segments? Were any of the repairs of paravalvar leak you have done in valves previously implanted with a continuous technique?

Ani
  ----- Original Message ----- 
  From: rwmfglycar at aol.com<mailto:rwmfglycar at aol.com> 
  To: OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com> 
  Sent: Saturday, April 07, 2007 4:49 PM
  Subject: Re: [HSF] Trip to Croatia


  Think Ani. 
  Assuming that the tensile strength and durability of the suture chosen is adequate to hold the closed valve in situ against the downstream pressure indefinitely, and that the knots are tied properly, then Paravalvar Leak is the consequence of one or more of the following factors :
  1) Too few suture connections between the tissue and the sewing ring (whether interrupted or continuous).
  2) Too little tissue encompassed by the suture, so that the tissue strength is inadequate to hold the closed valve in situ against the downstream pressure.
  3) General pathology of the tissue that makes it too weak even with a normal depth of suture to withstand the load it is supposed to carry.
  4) Local pathology of the tissue, with focal weakness that does the same as in 4) above.
  5) A sewing ring that does not allow healing of the host to the ring material. (many rings fit this category so that insertion is indefinitely dependent on the original sutures and some overgrowth rather than incorporation).
  6) A tissue annulus that does not heal to the sewing ring and may in addition abrade the sutures. (An inadequately debrided calcified annulus is an example of this. Note too that abrasion of the suture may take time).
  I would also make the following generalisations: 
  i) Small, trivial paravalvar leaks are common early (probably due to factor 1) above and often heal quite soon
  ii) Most significant paravalvar leaks are also evident early if you search for them and unless they produce hemolysis, tend to be followed until they have made the ventricle sick. 
  iii) The single biggest danger  of continuous suture technique is that if factors 1), 2), 3), 4) are present in one way or another, implying poor technique (including inadequate exposure), or poor analysis of the pathology, once the first loosening of the suture occurs the stress on the adjacent tissue/suture combination inevitably increases and tends to cause progressive pulling loose of the whole suture line.
  This, of course, is why users of continuous sutures took to making interruptions.
  If the causes are analysed in the way I am suggesting there is no general statement to be made that "the standard of care is replacement". In my time I replaced some and repaired some. In fact there were two cases in which cardiac surgeons had already replaced the valve for paravalvar leak in which, when they were sent to me with once again significant paravalvar leaks, I did succesful repairs that I know never recurred.
  I am intrigued by Prasanna's observation of a fractured prolene suture. 2-0 prolene does not do this unless it was damaged. I suspect the surgeon grabbed it with a clamp to pull the loops tight. I would not be surprised if the history shows some leak duringthe first 6 months after surgery.
  Bob
   
   
  -----Original Message-----
  From: anianyanwu at hotmail.com<mailto:anianyanwu at hotmail.com>
  To: OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com>
  Sent: Sat, 7 Apr 2007 9:01 AM
  Subject: Re: [HSF] Trip to Croatia


  Bojan/Prasanna

  Thanks for the clarification. My question regarding replacing the valve was 
  misunderstood. My question was that assuming you decided you had to explant the 
  valve and rereplace, would you then reuse the same explanted SE valve - with its 
  nine year history of reliability in the patient - or would you use a new non-SE 
  valve? 

  I would however argue with the logic (in general) to leave previously implanted 
  valves in situ. If your argument was to leave a time tested reliable valve which 
  is compatible with the patient in situ, how would it be logical to leave a 
  time-tested unreliable (because it has failed once) suture line in situ which 
  was cause of the patient's reoperation? It is true that the suture technique was 
  to blame, but then you have left a valve which in two-thirds of its 
  circumference relies on an insecure technique. If the suture technique is to 
  blame then does the whole suture line not need a cure? And if we chose to talk 
  of biology, the patient and suture line have shown incompatibility by failure of 
  part of the suture line (for whatever reason). Have we not lost an opportunity 
  to cure her of this problem? She remains at unquantifiable, but not 
  insignificant risk of paravalvar leakage, for the rest of her life - a risk that 
  could have been grossly reduced by rereplacement with interrupted sutures. I was 
  trained with the philosophy that the treatment for paravalvar leak is always 
  rereplacement as whatever factor caused the leak could precipitate either 
  failure of repair or new leakage - by definition one has to assume (even with 
  interrupted sutures) that the whole suture line is at risk. In training I saw 
  few patients who came back with leaks after attempted repair of paravalvar 
  defects. Of course if repairing the defect vs replacement was a life-death 
  decision, repair is preferable to embarking on a fatal or technically impossible 
  rereplacement, but I think it is correct to say that the standard of care should 
  be valve rereplacement (I assume so and stand to be corrected)? 

  Having worked at a hospital very close to Harley Street where her surgery was 
  performed (and with surgeons who operate in Harley Street), I will tell you that 
  we saw a LOT of mitral (and even aortic) reoperations on patients who had 
  continuous suture MVR. No data to prove but it is my conception that this by far 
  outnumbered (proportionally) those patients coming back with interrupted 
  sutures. Patients with continuous sutures were unique though because unlike most 
  interrupted paravalvar leaks which presented early after replacement, paravalvar 
  leaks after continuous sutures developed at any time after implantation from 
  days to years. We saw some continuous suture valves developing new leaks many 
  years after implant as was case in your patient. If she is young enough, any 
  part of the remaining suture can fail in the future and she will develop a new 
  leak (especially considering that SE sutures were placed in rereplacement 
  setting).

  For all the talk about data on the SE and non-inferiority, there is one problem 
  - who here would honestly have such a valve implanted on themselves or their 
  family? For all our talk, and maybe we are brainwashed by industry, we deep 
  inside do not see the two designs (ball and cage vs disc) as equivalent. I will 
  be the first to own up that I would not have a SE valve put in me even though I 
  accept (and have stated) there is no evidence it is inferior.

  Ani


  ----- Original Message ----- 
    From: bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr>> 
    To: OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com>> 
    Sent: Saturday, April 07, 2007 4:48 AM
    Subject: Re: [HSF] Trip to Croatia


    Ani ,
    to re-clarify , I do not have  a preconception  about the inferiority  of
    SE valve  at all. Quite the opposite , leaving that  valve  in place 
    was at least partially  motivated  by  the preconception that  the valve
    was good enough  to be left ( as Prasanna pointed out )  ,  there  was
    no problem  with  the valve  during the past  9 years , so the valve 
    was left  rather than  to face more dificult ( and  potentially
    dangerous) replacement. My  clarification  was directed  to  your
    suggestion that  the decision for primary implantation of SE valve ( and
    subsequent decision  not  to re-replace it) was motivated with "
    economic  constraints" in Croatia , which do not exist ( at least
    regarding the choice of valves) . In late 80's we switched to more
    "modern" ( and definitely more expensive ) valves , whether it made
    any benefit to our patients can still be debated.
    Regarding the preoperative plan , as the nature of  massive paravalvular
    leak was unclear , all options ( patching , replacement , additional
    sutures) were considered , and I think that Prasanna opted for the most 
    balanced solution.The last  question  about potential  reimplantation of
     another SE valve is  theoretical , as SE valve  has not been available
    in Croatia for almost 20 years. However , I honestly think that any 
    valve  would  do well in this  lady , and that the problem  was  of
    completely different nature which you toroughly described.
    It would be also very interesting  to see Hal's oppinion  on potential
    legal implications of  such suturing technique if this  happened in U.S.

    Bojan

    On 4/7/2007, "Ani Anyanwu" <anianyanwu at hotmail.com<mailto:anianyanwu at hotmail.com<mailto:anianyanwu at hotmail.com<mailto:anianyanwu at hotmail.com>>> 
  wrote:

    >Now that explains it - prasanna's description of continuous prolene used in a 
  reop MVR will sound as an odd choice of technique to many, but as anyone who 
  trained in London (like I did) would understand as there are numerous surgeons 
  who sadly still use this technique as method of choice for mitral valve 
  implantation. This partly arises because there is a school of surgery in London 
  that ascribes mainly to the (Cooley) philosophy that fast surgery and limited 
  cardiac ischemia has to be the goal in all procedures - for valve surgery this 
  means continuous sutures for all implants. I say sadly because there is evidence 
  that patients who have a continuous suture technique have a higher incidence of 
  paravalvar leakage - including data from presented but never published by the 
  London St George's group a decade ago.
    >
    >Interesting though that reading through the lines Bojan seems to imply that 
  SE is an inferior valve and suggests surprise that it was used in London in 1998 
  when it had been abandoned in Croatia 10 years earlier. If that is the 
  preconception therefore why would one keep an 'inferior' valve? It is more than 
  likely that the pre-operative plan was indeed to replace this valve and the 
  decision to repair the defect was one made intraoperatively. I would then ask 
  Bojan and Prasanna, assuming the decision had been to rereplace the valve would 
  they have reimplanted the SE or placed a bileaflet valve?
    >
    >SE valves were used in London at least till 2000. I am not sure why but I did 
  know of some surgeons stated advantages in the sewing ring and durability as the 
  basis. Indeed Murday and Treasure from London randomized almost 400 patients to 
  either a SE or a St Jude valve in both mitral and aortic positions between 1991 
  and 1997. This is one of few statistically powered randomized trials in cardiac 
  surgery. Incidentally this trial which was published in the Annals (2003) showed 
  no difference in valve related outcomes between the two groups. They conclude 
  that it is important that we do not base our comparisons on valve prosthesis on 
  historical control data - the outcomes of a SE valve in 1970 are different from 
  those in 2000. As Tom Treasure always said, assuming discs valves came first and 
  someone in 1995 suddenly invented the ball and cage a novel design which will 
  prevent jammed disc, surgeons will all embrace it and we would probably all be 
  placing SE valves now. That is why we have to scientifically study outcomes, 
  randomizing where necessary - as Hunter said "when I did the experiment the 
  result was different" - our preconceptions (of the 'archaic' SE) may not 
  necessarily reflect the truth. Interestingly though, despite finding that the 
  two valves were indifferent, the authors did not recommend continued use of SE 
  and as far as I know that group ceased implanting the valves after the trial 
  closed. This goes to say that there is a lot that is unsaid outside the realms 
  of data, results and evidence, and often it is these unspoken observations and 
  summations, rather than the evidence, that guide our choice of therapy.
    >
    >Ani
    >  ----- Original Message ----- 
    >  From: bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr<mailto:bbiocina at kbd.hr>>> 

    >  To: OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com>>> 

    >  Sent: Saturday, April 07, 2007 2:54 AM
    >  Subject: Re: [HSF] Trip to Croatia
    >
    >
    >  As Prasanna is  polite and nice ( and I am  little  less  of both of
    >  that) , I would just like to clarify: second  redo operation on patient 
    >  with Starr-Edwards  was done  at Harley Street ,London , UK ,  in 1998,
    >  (the reason  for op. was degenerated CE tissue valve) , when  and where 
    >  the type of  valve was chosen. Last  Starr-Edwards  valves were
    >  implanted in Croatia  in late 80's( being a registrar in general
    >  surgery I can still remember those operations).
    >  Other issues  have  been clearly  explained by Prasanna , nothing more to
    >  add.
    >
    >  Bojan
    >
    >  On 4/7/2007, "Prasanna Simha M" <prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com>>>> 
  wrote:
    >
    >  >I do not think there would be a problem of accessing another valve for
    >  >reimplantation in Croatia as the system is governmental paying and health
    >  >care is born by the Government.
    >  >There are three things that made me retain the valve.
    >  >1) The valve on inspection was pristine with no clot and actually what
    >  >worried me was there was not even a hint of pannus on the sewing rim.
    >  >2) The mechanism of leak was due to suture failure (I could see the frayed
    >  >suture with the ends popping out !! ) and had nothing to do with the 
  valve.
    >  >3) This patient had a very favorable event rate with the valve till the 
  leak
    >  >occurred. Some patients are "Thrombosers /Bleeders" and it is well known
    >  >that the highest event rate is in the first 18 months after implantation.
    >  >She was otherwise doing well till 9 months before. I am not so much 
  against
    >  >the Starr Edwards valve and frankly there is also equal literature as Ben
    >  >says showing good durability and function  so I am not inherently biased 
  to
    >  >replacing it.Also with the torque of the heart due to left hemidiaphragm
    >  >elevation replacement would not have also been very easy and I was content
    >  >in fixing the problem and did not want to "overdo" things.I feel that the
    >  >problem that occurred was due to use of a continuous suture technique in a
    >  >redo case were probably interrupted suture technique would have been more
    >  >appropriate.
    >  >Bojan will be sending me the scanned pictures of the CT and if you see it,
    >  >you will appreciate that just approaching and visualizing the valve was
    >  >difficult let alone operating on it.
    >  >Prasanna
    >  >
    >  >On 4/7/07, Tea Acuff <tacuff at swbell.net<mailto:tacuff at swbell.net<mailto:tacuff at swbell.net<mailto:tacuff at swbell.net<mailto:tacuff at swbell.net<mailto:tacuff at swbell.net<mailto:tacuff at swbell.net<mailto:tacuff at swbell.net>>>> 
  wrote:
    >  >>
    >  >> This trip was quite a feat, Prasanna. Your immediate results are highly
    >  >> commendable.
    >  >>
    >  >> The critiques, however, highlight one of the wrinkles of dialect that we
    >  >> discuss in various forms usually as evidence, authority or experience. 
  The
    >  >> problem is comparing each patient that we see to the populations or
    >  >> individual other patients. Medicine is face to face, or borrowing Dr.
    >  >> Frater's expression, one on one. Not that we should experience each 
  patient
    >  >> as if there is no connection whatsoever to the last or the many, but 
  each
    >  >> patient is as unique as each surgeon's capacity and context. It is 
  similar
    >  >> to the appellation of the infectious disease specialty (as we commonly 
  use
    >  >> in the US) instead of geographical medicine. TB in Tennessee is not TB 
  all
    >  >> over the world, nor is a rash. The latter moniker, geographical 
  medicine,
    >  >> expresses literally a whole new world view. As for infectious disease, 
  wait
    >  >> a while and the world will change around you. Cardiac surgery, while not 
  as
    >  >> dramatic geographically or temporally, likely has many of the same 
  lessons.
    >  >>
    >  >> We don't operate specifically on patients with mitral regurgiation, or
    >  >> even posterior leaflets, but specific (even if unknown) disease 
  etiologies
    >  >> and confirmations by surgeons in different systems with different 
  resources.
    >  >> In rheumatics it is likely that the posterior leaflet is the most 
  deformed
    >  >> and the least fixable by hacks like me. Ani has pointed out that a 
  variety
    >  >> of techniques have come, gone and persisted, but assuming the actual 
  result
    >  >> is dependent strictly based on technique or anatomical location, or even
    >  >> type of prothesis is a myopic fantasy. Prasanna gives very suitable 
  reasons
    >  >> to ignore our "best practices". Only his actual, observed results will
    >  >> justify his thinking, or his best practice, not my guidelines.
    >  >>
    >  >> The same journal that Tomas recently suggested (Canadian Journal of
    >  >> Cardiology March 2007?) had an article about ED evaluation of chest pain
    >  >> that dealt with the problems and successes of protocols, guidelines and
    >  >> scoring systems in the actual practice of matching specific patients to
    >  >> theoretical and actual populations. I thought it was more interesting 
  than
    >  >> the one that he recommended, because it was about an area that I could
    >  >> understand but not blinded by my own biases and information. Sometimes 
  we
    >  >> can not see what the others describe because we use the same words but
    >  >> actually have a different "dialect", ie use the same words to describe
    >  >> somewhat different situations. We tend to rest well knowing that we did 
  what
    >  >> the experts or our last success say. Our patients may rest better if we
    >  >> study each patient result that we encounter. High risk is often the 
  mirror
    >  >> image of poor selection.
    >  >>
    >  >> Nice job, Prasanna.
    >  >>
    >  >> Sorry for the lecture.
    >  >> tea
    >  >>
    >  >>
    >  >>
    >  >> ----- Original Message ----
    >  >> From: prasannasimha <prasannasimha at gmail.com<mailto:prasannasimha at gmailcom<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmailcom<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmailcom<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmailcom>>>>
    >  >> To: OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com>>>
    >  >> Sent: Friday, April 6, 2007 9:23:39 PM
    >  >> Subject: Re: [HSF] Trip to Croatia
    >  >>
    >  >>
    >  >> Taking her previous event rate and our experience in India with a Starr
    >  >> Edwards valve , I would really contest its "Higher" thrombogenicity. I
    >  >> can tell for sure that there have been less "fatal" events with this
    >  >> valve compared to  the newer ones. Usually any valve thrombosis with the
    >  >> Starr Edwards is "symptomatic"  and allows them to reach the Hospital
    >  >> such that thrombolysis can be instituted as "complete" valve choke is
    >  >> less often seen. In fact in India it was very popular compared to other
    >  >> mono/bileaflet valves for this very reason .
    >  >> I see a specific role for the Mitrofast in patients with retracted PML's
    >  >> in rheumatics where P3 retraction does not allow delamellation, old
    >  >> ladies with calcified MAC and PML pathology where posterior pathology
    >  >> may be more difficult to repair and salvage of some patients with
    >  >> attempted repairs where there is a failure of the repair . This
    >  >> technique could be a useful adjunct to a surgeon if used wisely and
    >  >> appropriately.
    >  >> Prasanna
    >  >>
    >  >> Ani Anyanwu wrote:
    >  >> > Prasanna
    >  >> >
    >  >> > Interesting narrative.
    >  >> >
    >  >> > I am keen to know your honest opinion of the Mitrofast having now
    >  >> witnessed it. It seems to me counterintuitive that one would repair the
    >  >> (more difficult) anterior leaflet and yet treat the posterior leaflet 
  with a
    >  >> device that allows successful repair where the surgeon is not skilled in
    >  >> repair. Surely if one can repair an anterior leaflet he can also repair 
  the
    >  >> posterior too rather than placing a prosthesis?
    >  >> >
    >  >> > Also while I acknowledge the economic constraints in Crotia may have
    >  >> forced it, in general would you recommend repair of dehiscence in a 
  patient
    >  >> with a SE valve coming back with paravalvar leak? Is this not a lost
    >  >> opportunity to switch to a less thrombogenic valve (if you believe the 
  SE is
    >  >> more thrombogenic that is)?
    >  >> >
    >  >> > Ani
    >  >> >   ----- Original Message -----
    >  >> >   From: prasannasimha<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com<mailto:prasannasimha at gmail.com>>>>
    >  >> >   To: OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com<mailto:OpenHeart-L at lists.hsforum.com>>>>
    >  >> ; ccm<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org<mailto:ccm-l at ccm-l.org>>>> 
  ; Med-Events<mailto:med-events at ccm-l.org<mailto:med-events at ccm-l.org<mailto:med-events at ccm-l.org<mailto:med-events at ccm-l.org<mailto:med-events at ccm-lorg<mailto:med-events at ccm-l.org<mailto:med-events at ccm-l.org<mailto:med-events at ccm-l.org>>>>
    >  >> >   Sent: Thursday, April 05, 2007 12:06 PM
    >  >> >   Subject: [HSF] Trip to Croatia
    >  >> >
    >  >> >
    >  >> >   On the invitation of Bojan Biocina, I had been to Hospital Dubrava ,
    >  >> >   Zagreb ,Croatia.
    >  >> >   I had the opportunity to see and experience another culture and
    >  >> interact
    >  >> >   with  surgeons from another land.
    >  >> >   All the members of the cardiac surgical team are avid followers of 
  the
    >  >> HSF.
    >  >> >   We did  quite a few interesting cases.(repairs, adult congenital and
    >  >> >   redo's).
    >  >> >   I had the opportunity to demonstrate the electrocautery maze there 
  and
    >  >> >   also the use of indigenous rings using material that they had at 
  hand
    >  >> (
    >  >> >   used split pieces of Goretex tube grafts) which are excellent.
    >  >> >   We had  a redo post subaortic membrane resection. I did an initial
    >  >> mini
    >  >> >   Konno procedure and when we weaned I found an unacceptable gradient 
  .
    >  >> On
    >  >> >   analysis of the TEE I saw the appearance of new SAM, mitral
    >  >> >   regurgitation and gradient in the upper part which failed to 
  disappear
    >  >> >   with removal of all inotropes and volume loading (which was 
  previously
    >  >> >   "Open" and so we went back and I did an extensive "Morrow" type" of
    >  >> >   resection after which the gradient came down to 15 mm Hg on pressure
    >  >> >   recording, the SAM and MR also disappeared.
    >  >> >
    >  >> >   There was another very sick lady who had multiple surgeries (OMV via 
  a
    >  >> >   left thoracotomy ( bioprostheses and a SE valve implantation). The
    >  >> last
    >  >> >   surgery was the SE implantation and she now had major paravalvar 
  leak,
    >  >> >   TR and also AFib. She was extremely sick and I was really wondering
    >  >> >   whether she needed emergent surgery at night.She also had left
    >  >> >   diaphragmatic paralysis and so we decided not to use a right
    >  >> thoracotomy
    >  >> >   in case we damage the right phrenic too !! As per my usual protocol 
  ,
    >  >> I
    >  >> >   did her with femoral arterial and venous cannula in place and backed
    >  >> up
    >  >> >   volume into the reservoir to allow the BP to drop to the 60's  while
    >  >> >   opening the sternum allowing the heart to fall back. I had given
    >  >> >   instructions to go on CPB if there is persistent difficulty in
    >  >> >   maintaining hemodynamics . With this method I am able to dissect the
    >  >> RV
    >  >> >   easily and can immediately go on CPB when the dissection becomes
    >  >> >   difficult.(With this  we can combine the advantages of both limiting
    >  >> CPB
    >  >> >   and using it to advantage when we want things to "collapse" as the
    >  >> >   situation demands.
    >  >> >   We dissected most of the "required" area  without CPB and then went 
  on
    >  >> >   CPB. Due to left diaphragmatic elevation the RA was in the position 
  of
    >  >> >   the  regular LA (the heart was torted - we had seen that too in the
    >  >> CT).
    >  >> >   We used a balloon cannula for the SVC and that did not matter so 
  much
    >  >> as
    >  >> >   we had vacuum assist. We  endoclamped the aorta with a Foley balloon
    >  >> >   after beating heart TV repair and right emaze lesions.
    >  >> >   On opening the LA transeptally, we found that the surgeon who did 
  the
    >  >> >   redo had used a continuous suture (3 suture Prolene technique) and 
  the
    >  >> >   prolene had unraveled off one third the annulus. I did not explant 
  the
    >  >> >   valve as there was no evidence of endocarditis and I did not have to
    >  >> >   patch the annulus (we were contemplating either valve reimplantation
    >  >> or
    >  >> >   patching the paravalvar leak with a double patch initially) as the
    >  >> >   mechanism was clear as I could see the frayed suture broken in the
    >  >> >   middle !!- there was also no evidence of previous endocarditis.
    >  >> >   Using liberal felt supplemetation and mattress sutures the leak was
    >  >> >   closed (In the meanwhile the balloon burst so I used intermittent
    >  >> >   dropping of flows at 22 Deg as this patient had AR (not requiring
    >  >> >   replacement   but significant enough to trouble us !!). The leak was
    >  >> >   tested intraop as thereAR leak allowed easy visualization of the
    >  >> >   original leak and also after suturing).
    >  >> >   We were able to come off CPB uneventfuly and she is extubated and
    >  >> doing
    >  >> >   well !!
    >  >> >
    >  >> >   Other cases done included 2 repairs including bileaflet prolapse
    >  >> >   (myxomatous) one ascending aortic replacement with David
    >  >> procedure  and
    >  >> >   also I got to see a Mitrofast implantation- incidentally this 
  patient
    >  >> on
    >  >> >   table had billeaflet prolapse so I placed artificial anterior chords
    >  >> and
    >  >> >   Bojan placed the Mitrofast and we got good coaptation.
    >  >> >   I did an elective  MVR on a lady who had some suspicion of SLE but 
  the
    >  >> >   Echo looked "rheumatic" on table did not fit into either and since 
  the
    >  >> >   "verrucous" lesions (confined only atrially) was bileaflet in nature 
  ,
    >  >> I
    >  >> >   felt it was not wise to attempt a repair (I thought that if it was
    >  >> >   mainly confined to the AML , I would be able to excise that and 
  patch
    >  >> >   that area) so we replaced that valve after reconfirming that the 
  valve
    >  >> >   would possibly require an extensive repair with possibility of
    >  >> >   questionable results in the long term.
    >  >> >
    >  >> >   This was a good experience and with international cooperation.
    >  >> >   This would not have been possible without the "invention" of the HSF
    >  >> by
    >  >> >   Marc Levinson and I should congratulate him for starting the list
    >  >> serve
    >  >> >   without which  this would never  been possible.
    >  >> >   I was extremely honored to be invited to conduct the workshop and
    >  >> share
    >  >> >   my views and opinions and also to learn new approaches and solutions
    >  >> to
    >  >> >   different problems and the wonderful case mix that I got to see.
    >  >> >   Prasanna
    >  >> >
    >  >> >
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    >  >
    >  >
    >  >--
    >  >Prasanna Simha M
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