[HSF] milrinone

[Prasanna Simha M]

There are  articles and especially in the pediatric age group for eg it has
been shown to be of benefit in the arterial switch and tetralogy etc.
Basically I believe its best use is in patients with pulmonary hypertension
and also RVdsfunction and in any condition where ventricular relaxation is
impaired as it is virtually the only inotrope with lusitropic action. I
would use it judiciously in these cases. Remember that itcan ccasue a fall
in SVR and so adequate volume loading (best given on the pump and warn the
perfusionist of a possible fall in the reservoir level -) In some cases it
may be of benefit to combine it with Norepinephrine.
Prasanna (in Leipzig at present)

On Dec 2, 2007 3:03 AM, james le <jamesle2007 at yahoo.com> wrote:

> Thanks Dr Prasanna,
>
>  Are there any studies which compared milrinone versus other inotropes
> which showed the superiority of milrinone regarding outcomes?
>
> Prasanna Simha M <prasannasimha at gmail.com> wrote:
>  Yes, works well in patients with dysfunctional RV's and stiff LV's. I use
> them in patients with severe PH, RV dysfunction and tetrology patients.
> They reduce inotropic usage and ICU time.
> Prasanna
>
>
> On 11/30/07, james le wrote:
> >
> > Is there any evidence of milrinone usage improving the out comes
> > following cardiac surgery?
> >
> > [I work in public hospital where there is some on going discussion about
> > its cost effectiveness]
> >
> >
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> Prasanna Simha M
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-- 
Prasanna Simha M