[HSF] milrinone

[Donald Ross]

We us it a lot and really think it is beneficial but I have no data.
If there were financial constraints  we would  undoubtedly use less  
but not give it up for serious myocardial dysfunction.
Don
On 03/12/2007, at 1:59 AM, Prasanna Simha M wrote:

> There are  articles and especially in the pediatric age group for  
> eg it has
> been shown to be of benefit in the arterial switch and tetralogy etc.
> Basically I believe its best use is in patients with pulmonary  
> hypertension
> and also RVdsfunction and in any condition where ventricular  
> relaxation is
> impaired as it is virtually the only inotrope with lusitropic  
> action. I
> would use it judiciously in these cases. Remember that itcan ccasue  
> a fall
> in SVR and so adequate volume loading (best given on the pump and  
> warn the
> perfusionist of a possible fall in the reservoir level -) In some  
> cases it
> may be of benefit to combine it with Norepinephrine.
> Prasanna (in Leipzig at present)
>
> On Dec 2, 2007 3:03 AM, james le <jamesle2007 at yahoo.com> wrote:
>
>> Thanks Dr Prasanna,
>>
>>  Are there any studies which compared milrinone versus other  
>> inotropes
>> which showed the superiority of milrinone regarding outcomes?
>>
>> Prasanna Simha M <prasannasimha at gmail.com> wrote:
>>  Yes, works well in patients with dysfunctional RV's and stiff  
>> LV's. I use
>> them in patients with severe PH, RV dysfunction and tetrology  
>> patients.
>> They reduce inotropic usage and ICU time.
>> Prasanna
>>
>>
>> On 11/30/07, james le wrote:
>>>
>>> Is there any evidence of milrinone usage improving the out comes
>>> following cardiac surgery?
>>>
>>> [I work in public hospital where there is some on going  
>>> discussion about
>>> its cost effectiveness]
>>>
>>>
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>>
>>
>>
>> --
>> Prasanna Simha M
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>
>
>
> -- 
> Prasanna Simha M
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