[HSF] milrinone

Prasanna Simha M prasannasimha at gmail.com
Mon Dec 3 21:13:53 EST 2007


lusitropic - failure of relaxation - go to the gym and lift an inappropriate
amount of weights and then your arms and legs have a loss of lusitrophy !!
Prasanna

On Dec 3, 2007 4:50 AM, Tea Acuff <tacuff at swbell.net> wrote:

> I tried to look up the meaning of lusitropic. Never could get a clear
> idea. I did find an interesting article for primary care physicians that
> claimed the treatment of diastolic heart failure (despite saying there was
> no clear defintion of diastolic heart failure) included the following:
>
> Treatment by present guidelines....Evidence class A
> Then a list of multiple therapies including beta blockers, diuretics,
> revascularization, etc. ....all listed as evidence class C!
>
> Imagine.
>
> tea
>
>
> ----- Original Message ----
> From: Prasanna Simha M <prasannasimha at gmail.com>
> To: OpenHeart-L at lists.hsforum.com
> Sent: Sunday, December 2, 2007 8:59:01 AM
> Subject: Re: [HSF] milrinone
>
> There are  articles and especially in the pediatric age group for eg it
> has
> been shown to be of benefit in the arterial switch and tetralogy etc.
> Basically I believe its best use is in patients with pulmonary
> hypertension
> and also RVdsfunction and in any condition where ventricular relaxation is
> impaired as it is virtually the only inotrope with lusitropic action. I
> would use it judiciously in these cases. Remember that itcan ccasue a fall
> in SVR and so adequate volume loading (best given on the pump and warn the
> perfusionist of a possible fall in the reservoir level -) In some cases it
> may be of benefit to combine it with Norepinephrine.
> Prasanna (in Leipzig at present)
>
> On Dec 2, 2007 3:03 AM, james le <jamesle2007 at yahoo.com> wrote:
>
> > Thanks Dr Prasanna,
> >
> >  Are there any studies which compared milrinone versus other inotropes
> > which showed the superiority of milrinone regarding outcomes?
> >
> > Prasanna Simha M <prasannasimha at gmail.com> wrote:
> >  Yes, works well in patients with dysfunctional RV's and stiff LV's. I
> use
> > them in patients with severe PH, RV dysfunction and tetrology patients.
> > They reduce inotropic usage and ICU time.
> > Prasanna
> >
> >
> > On 11/30/07, james le wrote:
> > >
> > > Is there any evidence of milrinone usage improving the out comes
> > > following cardiac surgery?
> > >
> > > [I work in public hospital where there is some on going discussion
> about
> > > its cost effectiveness]
> > >
> > >
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> > --
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> --
> Prasanna Simha M
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-- 
Prasanna Simha M


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