[HSF] Antiphospholipid Syndrome

[claudia miranda]

Dear listmembers:

First of all: are you sure this is antiphospholipid syndrome?
Has this guy undergone a full thrombophilia screening panel?Protein C, S,
ATIII, Leiden, prothrombin mutation, and MTHFR mutation plus dosing
of factor VIII, IX, X and XI ?
Second: has he received any heparin in the last six months?

I will send you a .pdf about anticoagulation in such patients off list.
Best.

Claudia Teles, MD
Hemostasis - Lamina Laboratories
Pro Cardiaco - Rio de Janeiro


2007/1/17, Nasser F. Abou'Seada <nfaabouseada at gmail.com>:
>
> Good question Hal !!!
>
> NFA
>
> > -----Original Message-----
> > From: openheart-l-bounces at lists.hsforum.com [mailto:openheart-l-
> > bounces at lists.hsforum.com] On Behalf Of hgrmd at aol.com
> > Sent: Wednesday, January 17, 2007 9:51 AM
> > To: OpenHeart-L at lists.hsforum.com
> > Subject: Re: [HSF] Antiphospholipid Syndrome
> >
> > Tohru,
> >   If you reread my post, you'll know that I have the same exact
> concerns.
> A
> > malignancy is certainly in the differential.  My plan is to get a fast
> cardiac MR to
> > further characterize the mass.  In addition, I will likely get a
> transcatheter biopsy.  All
> > in all, however, I think a man with a known phospholipid deficiency,
> history of DVT,
> > and ischemic toes is much more likely to have clot rather than tumor.
> >   Tohru, if it is clot, would you operate?
> > Hal
> >
> >
> > -----Original Message-----
> > From: toruasai at belle.shiga-med.ac.jp
> > To: OpenHeart-L at lists.hsforum.com
> > Sent: Wed, 17 Jan 2007 9:03 AM
> > Subject: Re: [HSF] Antiphospholipid Syndrome
> >
> >
> > Hal
> > I had a similar CT picture ( RA lumen occlusion by laminated clot like
> > tissue ) in young Japanese male patient a few years ago. I was about to
> > operate. The mass by trans-catheter biopsy turned out to be cardiac
> > malignant lymphoma. It dramatically responded to IV chemotherapy and
> > disappeared. I did not have to operate on him.
> >
> > My case may have nothing to do with yours. But I would recommend biopsy
> of
> > the mass by catheter. Since it shows unusual growth. By the way, why did
> you
> > know the mass was clot?
> > --
> > Tohru Asai
> >
> > > I  might consider a transjugular
> > > biopsy. If possible, I think the  clot needs to be removed and a maze
> carried
> > > out.
> > >  However, I'm unsure  how to handle the perioperative anticoagulation.
> >
> >
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