[HSF] Allopurinol

[Salerno, Tomas]

best treatment for ischemia-reperfusion injury is prevention.... the only method todate is perfusion
 
Tomas

________________________________

From: openheart-l-bounces at lists.hsforum.com on behalf of prasannasimha
Sent: Sun 1/21/2007 8:41 PM
To: OpenHeart-L at lists.hsforum.com
Subject: Re: [HSF] Allopurinol



Hal there were some studies documenting its efficacy in children and
mostly lambs and pigs. How much of it could be extended to human adults
is  a bit of the problem. As I said there is some literature and I will
dig it out (Bit busy today so will do it when I have the time)
Prasanna
Hgrmd at aol.com wrote:
> Dear Sherman,
>   Where is the clinical evidence that allopurinol is of any benefit in 
> treating intraop myocardial damage?  I assume it theoretically diminishes 
> reperfusion damage.  Again, in the absence of blinded, randomized studies,  how do you
> know it does anything?
> Hal
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