[HSF] HIT and CPB

[Claudia Teles]

We have similar problems here with HIT patients needing urgent
intervention. Can you share references about epoprostanol use in this
setting?
Our regulatory agency has not approved any of the DTIs yet.
We do it against the law, but I imagine this will change in a very near
future.

Best,

Claudia Teles


2007/6/2, EPS-CCV <epsccv at arrakis.es>:
>
> Dr. Teles
>
> Neither intraoperative nor postop thrombotic complications were
> encountered. The follow up 3 months later didn't show any thrombosis
> incidence neither there were clinical findings.
>
> I agree, the patient will be sensitive to heparin for the next 6 months
> after receiving the epoprostanol but we didn't have another option. The
> surgery indication was urgent (cardiac transplant, endocarditis, ...) in all
> cases.
> If the TAS Analyzer were available here, anticoagulation with lepirudin
> and on-line determination of the Ecarin Clotting Time during CPB would be my
> first choice, of course.
>
> Enrique P. de la Sota, FECTS
> Madrid - Spain
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-- 
Claudia Teles
Hemostasis Section - Instituto Estadual de Cardiologia Aloysio de Castro
Hemostasis Lab coordinator - Diagnosticos da America