[HSF] Aprotinin

[Michael Firstenberg]

I too will miss aprotinin since I really believed in it for my high risk
patients.

But, I think the larger issues are the personal vendettas again drugs in
which people push their careers often end up doing more harm than good.
But, hey - they keep the lawyers happy.  Just about everything that we do
and use has major risks associated with it (duh) - so are we just going to
start pulling drugs off the market one by one?


On 11/6/07, psimha <prasannasimha at gmail.com> wrote:
>
> Ajit, from anecdotal personal experience I feel tranexamicacid is better
> than epsilon aminocaproic acid. We used to use both but I now prefer
> tranexamic acid = 10mg/Kg before CPB 10 mg/Kg on pump and 10 mg/Kg after
> CPB. There are various schedules ranging from 10 - 400 mg/Kg
> Prasanna
> Ajit Damle wrote:
> > I for one, regret the passing of aprotinin. Even if it comes back on the
> > market, it will be tainted and may not see its glory days again.
> > Interestingly, according to NYT, half of the total prescriptions were in
> the
> > US. With sales of some 240 million dollars a year, it was not one of top
> 10
> > best selling drugs for Bayer.
> >
> > Will the members describe their personal experience of amicar, including
> > dosing? I have read the literature on it, and now want to hear from
> actual
> > users.
> >
> > Thanks!
> >
> > Ajit Damle
> >
> > I guess with Aprotinin gone, that is one topic less to discuss at our
> STS
> > dinner!
> >
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