[HSF] Re: ENHANCE Trial

[Michael Firstenberg]

I think these studies and results are going to become more common..... the
closer and closer ties with industry, the financial and other incentives,
reputations, frequent flier miles, etc that are at stake will further bring
to light to any and all biases.  It is interesting that in a study (not any
in particular - but more the lingo) that shows, after looking at thousands
of patients the results show Drug A is associated with a 0.5% complication
rate vs 1.0% is called 50% better and ergo.  We will be reading more and
more about these studies in the Times, WSJ, CNN than in the medical
literature - in part that is where the news is

There needs to be a little reality testing - the scientific method, process,
and review process areclearly tranished by the hoopla and shell games that
are played out.  There is too much at stake these days - and we are all
guilty to some degree.

-michael



On 2/1/08, Prasanna Simha M <prasannasimha at gmail.com> wrote:
>
> I was always worried about the widespread use of Ezetimibe and the
> reckless
> unsubstantiated promotion of it.
> Prasanna
>
> On Feb 2, 2008 10:01 AM, alsadd <alsadd at ksu.edu.sa> wrote:
>
> > Dear Forum Members:
> >
> >
> >
> > Any thoughts on ENHANCE study that is coming to light It has engendered
> > considerable controversy because, while the study was concluded almost
> two
> > years ago, the release of its results has been greatly (and famously)
> > delayed. There has been a strong and growing suspicion that the trial
> did
> > not come out the way the sponsors wanted it to, and that the delay has
> > been
> > for the purpose of trying to salvage something positive before releasing
> > the
> > results. Indeed, this suspicion recently has led to an investigation by
> > Congress. I understand it questions a lot of held belief on cholesterol
> > lowering drugs and hyperlipidemia in general. Your thoughts please
> >
> >
> >
> >
> >
> > Ahmed
> >
> >
> >
> >
> >
> >
> >
> >
> >
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>
> --
> Prasanna Simha M
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