[HSF] To "T" or not to "T"

Prasanna Simha M prasannasimha at gmail.com
Wed Jan 2 17:19:51 EST 2008


How long do you give Coumadin for ?
Prasanna

On Jan 2, 2008 5:14 PM, <zzhoumd at pol.net> wrote:

>
> It was my observation. I usually see vein grafts looked better if they are
> on coumadin for some reason.
>
> Z Zhou
>
> Sent via BlackBerry by AT&T
>
> -----Original Message-----
> From: Ben Bidstrup <benjamin.bidstrup at bigpond.com>
>
> Date: Wed, 2 Jan 2008 18:54:16
> To:OpenHeart-L at lists.hsforum.com
> Subject: Re: [HSF] To "T" or not to "T"
>
>
> There was the French study EPPAC 1991, which looked at the use Vit K
> A + persantin and Vit K A without persantin. Rates were pretty grim!
>
> >I think there was data to show that adding coumadin did not actually help
> in
> >early vein graft closure and the only thing that really helped was
> Aspirin
> >within 6 hours of surgery.
> >Prasanna
> >
> >On Dec 19, 2007 3:21 AM, Zhandong Zhou <zzhoumd at pol.net> wrote:
> >
> >>
> >>  The early vein graft failures are usually due to poor vein quality,
> >>  kinking or slow blood flow which forms thrombus inside the vein. You
> do not
> >>  usually see thrombus inside arterial graft. Kinking is also less
> common with
> >>  arterial graft. I think coumadin is better than plavix in preventing
> vein
> >>  graft closure in early post op period.
> >>
> >>  Z Zhou
> >>
> >>
> >>  ----- Original Message -----
> >>  From: "Tea Acuff" <tacuff at swbell.net>
> >>  To: <OpenHeart-L at lists.hsforum.com>
> >>  Sent: Monday, December 17, 2007 2:46 PM
> >>  Subject: Re: [HSF] To "T" or not to "T"
> >>
> >>
> >>  > How is this different than the "causes" we place on Vein graft
> failure?
> >>  >
> >>  > tea
> >>  >
> >>  >
> >>  > ----- Original Message ----
> >>  > From: "zzhoumd at pol.net" <zzhoumd at pol.net>
> >>  > To: OpenHeart-L at lists.hsforum.com
> >>  > Sent: Monday, December 17, 2007 6:45:38 AM
> >>  > Subject: Re: [HSF] To "T" or not to "T"
> >>  >
> >>  >
> >>  > In my experience and talk to the interventional cardiologists,
> arterial
> >>  graft failure is mainly due to technical failure or competitive flow.
> If one
> >>  branch become string, there is a reason for it.
> >>  >
> >>  > Z Zhou
> >>  >
> >>  > Sent via BlackBerry by AT&T
> >>  >
> >>  > -----Original Message-----
> >>  > From: Donald Ross <donross at bigpond.com>
> >>  >
> >>  > Date: Mon, 17 Dec 2007 15:54:01
> >>  > To:OpenHeart-L at lists.hsforum.com
> >>  > Subject: Re: [HSF] To "T" or not to "T"
> >>  >
> >>  >
> >>  > Tea,
> >>  > For  the LAD I use a SVG form the aorta ( non-clamped of course) and
> >>  > for other arteries I mostly don't graft if the lesion looks like  it
> >>  > would be amenable to stenting should it cause trouble in the future.
> >>  > Don
> >>  >
> >>  > On 17/12/2007, at 3:34 PM, Tea Acuff wrote:
> >>  >
> >>  >> And what do you do with other 50-75% lesions in large distribution
> >>  >> vessels?
> >>  >>
> >>  >> tea
> >>  >>
> >>  >>
> >>  >> ----- Original Message ----
> >>  >> From: Donald Ross <donross at bigpond.com>
> >>  >> To: OpenHeart-L at lists.hsforum.com
> >>  >> Sent: Sunday, December 16, 2007 10:13:39 PM
> >>  >> Subject: Re: [HSF] To "T" or not to "T"
> >>  >>
> >>  >> Tohru,
> >>  >> Nobody can argue with surgeons who has such a high incidence of
> early
> >>  >> recaths as yourself.
> >>  >> However, I was intrigued by your observation that the lima to LAD
> was
> >>  >> more likely to go down distally  if it supported a T graft.
> >>  >> How often do you see this and are you sure the cause wasn't a non
> >>  >> significant LAD lesion?
> >>  >>
> >>  >> This is an important question for me as I have put 944 arteries
>  onto
> >  > >> the LMA as T grafts. ( 617 radials, the rest rimas )
> >>  >> I only get a recath if the clinical result is sub-optimal and
> >>  >> fortunately that is rare. ( Usually the grafts are patent)
> >>  >> If, as you say, there are a lot of graft occlusions which have no
> >>  >> clinical consequence then I probably have my fair share.
> >>  >> Hopefully they are associated with non significant lesions which
> >>  >> explains my blissful ignorance.
> >>  >> Don
> >>  >>
> >>  >>
> >>  >>> Dave
> >>  >>> I appreciate your detailed comment. I agree in-situ RIMA is better
> >>  >>> than RGEA
> >>  >>> but in-situ RIMA has limitation to reach target sites, such as PDA
> >>  >>> and low
> >>  >>> marginals in many patients. These targets are not good for in-situ
> >>  >>> RIMA but
> >>  >>> it consistently reaches anywhere in LAD and proximal parts of
> >>  >>> marginal and
> >>  >>> ramus ( via oblique sinus). RIMA's patency is reported to be
> >>  >>> excellent, as
> >>  >>> good as LIMA's, when it is used in in-situ fashion for grafting
> left
> >>  >>> coronary territories. And free RIMA is not consistently as good as
> >>  >>> in-situ
> >>  >>> LIMA. So free RIMA branching off LIMA is not the best. I can tell
> >>  >>> you that
> >>  >>> even I see a few cases of distal LIMA after giving RIMA off became
> >  > >>> string at
> >>  >>> a few years after CABG. Whereas in-situ RIMA-LAD, in-situ LIMA-OM,
> >>  >>> and
> >>  >>> in-situ RIMA-OM are consistently good in mid and long term. This
> is
> >>  >>> not only
> >>  >>> my opinion, but most Japanese surgeons ( who live in a strange
> >>  >>> country) know
> >>  >>> it as a sort of common sense with watching many angiograms, I
> guess.
> >>  >>>
> >>  >>> I tell you that there were many patient recovering uneventfully
> >>  >>> with their
> >>  >>> postop angiogram demonstrating graft occlusions! So how can you
> >>  >>> know you are
> >>  >>> doing all right. I personally could achieve more than 95% patency
> >>  >>> including
> >>  >>> vein graft in early postop angiograms, mostly due to avoiding
> >>  >>> multi-branching composite configuration.
> >>  >>>
> >>  >>> I am aware that some are concerned about RIMA crossing midline
> >>  >>> anteriorly,
> >>  >>> but I don't mind to perform resternotomy ( actually did several
> >>  >>> cases for
> >>  >>> redo cab, aortic arch, AVR, mitral, tricuspid cases) as long as I
> >>  >>> did the
> >>  >>> first operation. I usually make vertical slit hole just anterior
> to
> >>  >>> SVC to
> >>  >>> enter pericardial space, in-situ RIMA easily reach distal LAD
> >>  >>> almost always.
> >>  >>> They did very well without entry problem at all in my experience.
> >>  >>> Surprisingly skeletonized IMA and GEA conduits looked as if they
> >>  >>> had been
> >>  >>> harvested yesterday. I recommend you not to make y composite LIMA
> >>  >>> and RIMA
> >>  >>> routinely. I know it is not as good as you expect from my
> "strange"
> >>  >>> upside
> >>  >>> down countryman view.
> >>  >>>
> >>  >>> Problems of arterial conduits are more related to flow
> competition.
> >>  >>> Once it
> >>  >>> stringed, nobody can tell that it may come back when the native
> >>  >>> stenosis
> >>  >>> becomes critical. There are a few reports of re-growing of "string
> >>  >>> sign",
> >>  >>> but clinically many recurred angina or MACE in real (strange)
> world.
> >>  >>>
> >>  >>> Only 75% stenosis of proximal RCA is not consistently good for any
> >>  >>> arterial
> >>  >>> conduits. I had seen many early postop angiograms of shrinked
> RIMA,
> >>  >>> RA,
> >>  >>> RGEA. Obviously saphenous vein is the best in the situation,
> unless
> >>  >>> you tie
> >>  >>> off RCA, which I have never done.
> >>  >>>
> >>  >>> Well, my logic became too long! In summary, I often do
> >>  >>> RIMA,LIMA,GEA all
> >>  >>> in-situ skeletonized with some sequential graftings to young but
> >>  >>> severe
> >>  >>> diffuse 3vessel disease. SV is still useful in moderately stenotic
> >>  >>> large
> >>  >>> target vessels or hemodynamically unstable bad urgent cases.
> >>  >>> ---
> >>  >>> Tohru
> >>  >>>
> >>  >>>
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> >
> >
> >
> >--
> >Prasanna Simha M
> >_______________________________________________
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>
> --
> Ben Bidstrup FRACS FRCSEd FEBCTS
> Consultant Cardiothoracic Surgeon
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-- 
Prasanna Simha M


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