[HSF] To "T" or not to "T"

Tea Acuff tacuff at swbell.net
Fri Jan 4 16:22:19 EST 2008


Which do you think was the "operative" variable?
;)

tea


----- Original Message ----
From: Ben Bidstrup <benjamin.bidstrup at bigpond.com>
To: OpenHeart-L at lists.hsforum.com
Sent: Wednesday, January 2, 2008 2:54:16 AM
Subject: Re: [HSF] To "T" or not to "T"

There was the French study EPPAC 1991, which looked at the use Vit K 
A + persantin and Vit K A without persantin. Rates were pretty grim!

>I think there was data to show that adding coumadin did not actually help in
>early vein graft closure and the only thing that really helped was Aspirin
>within 6 hours of surgery.
>Prasanna
>
>On Dec 19, 2007 3:21 AM, Zhandong Zhou <zzhoumd at pol.net> wrote:
>
>>
>>  The early vein graft failures are usually due to poor vein quality,
>>  kinking or slow blood flow which forms thrombus inside the vein. You do not
>>  usually see thrombus inside arterial graft. Kinking is also less common with
>>  arterial graft. I think coumadin is better than plavix in preventing vein
>>  graft closure in early post op period.
>>
>>  Z Zhou
>>
>>
>>  ----- Original Message -----
>>  From: "Tea Acuff" <tacuff at swbell.net>
>>  To: <OpenHeart-L at lists.hsforum.com>
>>  Sent: Monday, December 17, 2007 2:46 PM
>>  Subject: Re: [HSF] To "T" or not to "T"
>>
>>
>>  > How is this different than the "causes" we place on Vein graft failure?
>>  >
>>  > tea
>>  >
>>  >
>>  > ----- Original Message ----
>>  > From: "zzhoumd at pol.net" <zzhoumd at pol.net>
>>  > To: OpenHeart-L at lists.hsforum.com
>>  > Sent: Monday, December 17, 2007 6:45:38 AM
>>  > Subject: Re: [HSF] To "T" or not to "T"
>>  >
>>  >
>>  > In my experience and talk to the interventional cardiologists, arterial
>>  graft failure is mainly due to technical failure or competitive flow. If one
>>  branch become string, there is a reason for it.
>>  >
>>  > Z Zhou
>>  >
>>  > Sent via BlackBerry by AT&T
>>  >
>>  > -----Original Message-----
>>  > From: Donald Ross <donross at bigpond.com>
>>  >
>>  > Date: Mon, 17 Dec 2007 15:54:01
>>  > To:OpenHeart-L at lists.hsforum.com
>>  > Subject: Re: [HSF] To "T" or not to "T"
>>  >
>>  >
>>  > Tea,
>>  > For  the LAD I use a SVG form the aorta ( non-clamped of course) and
>>  > for other arteries I mostly don't graft if the lesion looks like   it
>>  > would be amenable to stenting should it cause trouble in the future.
>>  > Don
>>  >
>>  > On 17/12/2007, at 3:34 PM, Tea Acuff wrote:
>>  >
>>  >> And what do you do with other 50-75% lesions in large distribution
>>  >> vessels?
>>  >>
>>  >> tea
>>  >>
>>  >>
>>  >> ----- Original Message ----
>>  >> From: Donald Ross <donross at bigpond.com>
>>  >> To: OpenHeart-L at lists.hsforum.com
>>  >> Sent: Sunday, December 16, 2007 10:13:39 PM
>>  >> Subject: Re: [HSF] To "T" or not to "T"
>>  >>
>>  >> Tohru,
>>  >> Nobody can argue with surgeons who has such a high incidence of early
>>  >> recaths as yourself.
>>  >> However, I was intrigued by your observation that the lima to LAD was
>>  >> more likely to go down distally  if it supported a T graft.
>>  >> How often do you see this and are you sure the cause wasn't a non
>>  >> significant LAD lesion?
>>  >>
>>  >> This is an important question for me as I have put 944 arteries   onto
>  > >> the LMA as T grafts. ( 617 radials, the rest rimas )
>>  >> I only get a recath if the clinical result is sub-optimal and
>>  >> fortunately that is rare. ( Usually the grafts are patent)
>>  >> If, as you say, there are a lot of graft occlusions which have no
>>  >> clinical consequence then I probably have my fair share.
>>  >> Hopefully they are associated with non significant lesions which
>>  >> explains my blissful ignorance.
>>  >> Don
>>  >>
>>  >>
>>  >>> Dave
>>  >>> I appreciate your detailed comment. I agree in-situ RIMA is better
>>  >>> than RGEA
>>  >>> but in-situ RIMA has limitation to reach target sites, such as PDA
>>  >>> and low
>>  >>> marginals in many patients. These targets are not good for in-situ
>>  >>> RIMA but
>>  >>> it consistently reaches anywhere in LAD and proximal parts of
>>  >>> marginal and
>>  >>> ramus ( via oblique sinus). RIMA's patency is reported to be
>>  >>> excellent, as
>>  >>> good as LIMA's, when it is used in in-situ fashion for grafting left
>>  >>> coronary territories. And free RIMA is not consistently as good as
>>  >>> in-situ
>>  >>> LIMA. So free RIMA branching off LIMA is not the best. I can tell
>>  >>> you that
>>  >>> even I see a few cases of distal LIMA after giving RIMA off became
>  > >>> string at
>>  >>> a few years after CABG. Whereas in-situ RIMA-LAD, in-situ LIMA-OM,
>>  >>> and
>>  >>> in-situ RIMA-OM are consistently good in mid and long term. This is
>>  >>> not only
>>  >>> my opinion, but most Japanese surgeons ( who live in a strange
>>  >>> country) know
>>  >>> it as a sort of common sense with watching many angiograms, I guess.
>>  >>>
>>  >>> I tell you that there were many patient recovering uneventfully
>>  >>> with their
>>  >>> postop angiogram demonstrating graft occlusions! So how can you
>>  >>> know you are
>>  >>> doing all right. I personally could achieve more than 95% patency
>>  >>> including
>>  >>> vein graft in early postop angiograms, mostly due to avoiding
>>  >>> multi-branching composite configuration.
>>  >>>
>>  >>> I am aware that some are concerned about RIMA crossing midline
>>  >>> anteriorly,
>>  >>> but I don't mind to perform resternotomy ( actually did several
>>  >>> cases for
>>  >>> redo cab, aortic arch, AVR, mitral, tricuspid cases) as long as I
>>  >>> did the
>>  >>> first operation. I usually make vertical slit hole just anterior to
>>  >>> SVC to
>>  >>> enter pericardial space, in-situ RIMA easily reach distal LAD
>>  >>> almost always.
>>  >>> They did very well without entry problem at all in my experience.
>>  >>> Surprisingly skeletonized IMA and GEA conduits looked as if they
>>  >>> had been
>>  >>> harvested yesterday. I recommend you not to make y composite LIMA
>>  >>> and RIMA
>>  >>> routinely. I know it is not as good as you expect from my "strange"
>>  >>> upside
>>  >>> down countryman view.
>>  >>>
>>  >>> Problems of arterial conduits are more related to flow competition.
>>  >>> Once it
>>  >>> stringed, nobody can tell that it may come back when the native
>>  >>> stenosis
>>  >>> becomes critical. There are a few reports of re-growing of "string
>>  >>> sign",
>>  >>> but clinically many recurred angina or MACE in real (strange) world.
>>  >>>
>>  >>> Only 75% stenosis of proximal RCA is not consistently good for any
>>  >>> arterial
>>  >>> conduits. I had seen many early postop angiograms of shrinked RIMA,
>>  >>> RA,
>>  >>> RGEA. Obviously saphenous vein is the best in the situation, unless
>>  >>> you tie
>>  >>> off RCA, which I have never done.
>>  >>>
>>  >>> Well, my logic became too long! In summary, I often do
>>  >>> RIMA,LIMA,GEA all
>>  >>> in-situ skeletonized with some sequential graftings to young but
>>  >>> severe
>>  >>> diffuse 3vessel disease. SV is still useful in moderately stenotic
>>  >>> large
>>  >>> target vessels or hemodynamically unstable bad urgent cases.
>>  >>> ---
>>  >>> Tohru
>>  >>>
>>  >>>
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>
>--
>Prasanna Simha M
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-- 
Ben Bidstrup FRACS FRCSEd FEBCTS
Consultant Cardiothoracic Surgeon
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